Age: 35
Occupation: Comedienne, memoirist, TV host
Previous TIME 100 Appearances: 0
Handler's Are You There Vodka? It's Me, Chelsea was a runaway best-seller; her latest book, Chelsea Chelsea Bang Bang, out this year, has followed suit. Handler's willingness to take on any subject for comic effect and to say the unsayable has won her legions of fans and loyal readers.